A spectrophotometric micromethod for the study of theophylline pharmacokinetics in children with bronchial asthma

A spectrophotometric micromethod for determination of theophylline in the blood is proposed. Theophylline pharmacokinetics was studied by the method in 71 children with bronchial asthma. Doses and the number of administrations were selected individually for 45 patients under control of blood plasma...

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Published in:	Farmakologiia i toksikologiia Vol. 49; no. 5; p. 27
Main Authors:	Gavalov, S M, Ivanova, T A, Kaznacheeva, L F, Smirnova, L P, Slabuko, P A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-09-1986
Subjects:	Adolescent Aminophylline - administration & dosage Aminophylline - blood Asthma - blood Child Child, Preschool Dose-Response Relationship, Drug Humans Infant Kinetics Male Spectrophotometry, Ultraviolet - methods Theophylline - administration & dosage Theophylline - blood Time Factors
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Abstract	A spectrophotometric micromethod for determination of theophylline in the blood is proposed. Theophylline pharmacokinetics was studied by the method in 71 children with bronchial asthma. Doses and the number of administrations were selected individually for 45 patients under control of blood plasma theophylline concentration. Good clinical results were obtained.
AbstractList	A spectrophotometric micromethod for determination of theophylline in the blood is proposed. Theophylline pharmacokinetics was studied by the method in 71 children with bronchial asthma. Doses and the number of administrations were selected individually for 45 patients under control of blood plasma theophylline concentration. Good clinical results were obtained.
Author	Ivanova, T A Gavalov, S M Smirnova, L P Slabuko, P A Kaznacheeva, L F
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BackLink	https://www.ncbi.nlm.nih.gov/pubmed/3770169$$D View this record in MEDLINE/PubMed
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DocumentTitleAlternate	Issledovanie spektrofotometricheskim mikrometodom farmakokinetiki teofillina u deteĭ s bronkhial'noĭ astmoĭ
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SubjectTerms	Adolescent Aminophylline - administration & dosage Aminophylline - blood Asthma - blood Child Child, Preschool Dose-Response Relationship, Drug Humans Infant Kinetics Male Spectrophotometry, Ultraviolet - methods Theophylline - administration & dosage Theophylline - blood Time Factors
Title	A spectrophotometric micromethod for the study of theophylline pharmacokinetics in children with bronchial asthma
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