The effect of progesterone and tamoxifen on EGF-dependent activation of phospholipid turnover in uterine and breast tumor cells

The in vitro effects of the epidermal growth factor (EGF) and progesterone on phospholipid turnover in cells of 19 human adenocarcinomas (postsurgical material) have been studied. In 58% of tumours EGF increased the 32P incorporation into two basic cell phospholipids--phosphatidylcholine and phospho...

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Bibliographic Details

Published in:	Biokhimiia (Moscow, Russia) Vol. 58; no. 6; p. 967
Main Authors:	Krasil'nikov, M A, Shatskaia, V A, Bassalyk, L S
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-06-1993
Subjects:	Adenocarcinoma - metabolism Breast Neoplasms - metabolism Chromatography, Thin Layer Epidermal Growth Factor - pharmacology Estradiol - pharmacology Female Humans Phospholipids - metabolism Phosphorus Radioisotopes Progesterone - pharmacology Tamoxifen - pharmacology Tetradecanoylphorbol Acetate - pharmacology Tumor Cells, Cultured Uterine Neoplasms - metabolism
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