Effect of synaptic activation and serotonin application on the calcium current in Helix neurons

Changes in inward calcium current observed on the background of postsynaptic currents have been studied in snail neurons under voltage clamp conditions. It is shown that when inhibitory or excitatory postsynaptic current developed, the calcium current reversibly decreased. Application of serotonin t...

Full description

Saved in:

Bibliographic Details
Published in:	Neirofiziologiia = Neurophysiology Vol. 18; no. 1; p. 77
Main Authors:	Kononenko, N I, Shcherbatko, A D
Format:	Journal Article
Language:	Russian
Published:	Ukraine 1986
Subjects:	Animals Calcium - metabolism Cell Membrane Permeability - drug effects Membrane Potentials - drug effects Nervous System - drug effects Nervous System Physiological Phenomena Serotonin - pharmacology Synapses - physiology Synaptic Transmission
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Changes in inward calcium current observed on the background of postsynaptic currents have been studied in snail neurons under voltage clamp conditions. It is shown that when inhibitory or excitatory postsynaptic current developed, the calcium current reversibly decreased. Application of serotonin to the neuronal soma has also led to a reversible block of the calcium current. Possible cellular mechanisms involved in the changes under study and their putative physiological role are discussed.
ISSN:	0028-2561