Enhancement of antiexudative activity of liposomes using unsaturated fatty acids

The paper shows it possible to increase the antiexudative effect of lecithin cholesterol liposomes by incorporating additional amounts of unsaturated fatty acids (UFA). A way of incorporating UFA into the liposomal membrane substantially affects the effect under study. A mere mixing of ingredients (...

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Bibliographic Details
Published in:	Patologicheskaia fiziologiia i eksperimental'naia terapiia no. 3; p. 18
Main Authors:	Borodulina, E M, Kreĭnes, V M
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-07-1996
Subjects:	Animals Exudates and Transudates Fatty Acids, Unsaturated - chemistry Liposomes - chemistry Membranes, Artificial Rats Rats, Wistar
Online Access:	Get more information
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Summary:	The paper shows it possible to increase the antiexudative effect of lecithin cholesterol liposomes by incorporating additional amounts of unsaturated fatty acids (UFA). A way of incorporating UFA into the liposomal membrane substantially affects the effect under study. A mere mixing of ingredients (UFA and liposomes) caused no significant changes in exudative processes. The direct incorporation of UFA into the membrane of vesicles during their formation in the same molar ratios not only considerably enhanced the dehydrating effect of lecithin cholesterol liposomes, but showed the pronounced effect of true dehydration which could be recorded.
ISSN:	0031-2991