Adverse effects on the respiratory system in textile printing sprayers

• Published in: Revista clínica espanõla Vol. 196; no. 3; p. 157
• Main Authors: Solé Jover, A, b1rtínez Francés, M E, Cordero Rodríguez, P J, Vallterra Musoles, J, Macián Gisbert, V
• Format: Journal Article
• Language: Spanish
• Published: Spain 01-03-1996
• Subjects: Adolescent; Adult; Biopsy; Bronchial Hyperreactivity - diagnosis; Cryptogenic Organizing Pneumonia - chemically induced; Cryptogenic Organizing Pneumonia - diagnosis; Cryptogenic Organizing Pneumonia - pathology; Female; Humans; Lung - pathology; Lung Diseases - chemically induced; Lung Diseases - diagnosis; Lung Diseases - pathology; Male; Occupational Diseases - chemically induced; Occupational Diseases - diagnosis; Occupational Diseases - pathology; Paint - adverse effects; Pulmonary Fibrosis - chemically induced; Pulmonary Fibrosis - diagnosis; Pulmonary Fibrosis - pathology; Respiratory Function Tests; Solvents - adverse effects; Syndrome; Textile Industry
• ISSN: 0014-2565

To study the initial respiratory effects and those observed 18 months later after the inhalation of toxic and irritant substances in textile aerography workers.
Seventeen patients (14 women and 3 men), with a mean age of 21 years (range: 18-38).
Initially, pulmonary effects were assessed by pathological (transbronchial biopsy and/or video-thoracoscopy) and functional findings [spirometry with lung volumes and study of diffusion capacity of CO (DLCO)]. Eighteen months later a challenge bronchial test with histamine was performed.
Forty-one per cent of patients had pathologic lesions with intraalveolar fibrin, 35% had minimal non-specific lesions, 18% bronchiolitis obliterans with organized pneumonia (BOOP) and 6% pulmonary fibrosis and BOOP. Functional respiratory test showed two patients with a slight restrictive pattern, one patient with very severe restriction and six patients with low DLCO. The challenge tests was positive for 59% of patients.
After the massive inhalation of irritant and/or toxic substances, patients presented different types of pathological response at pulmonary level. In our workers histological repairing lesions--of high or low degree--were found, BOOP being the lesions observed most frequently, and different patterns of functional involvement. Fifty-nine per cent of cases developed non-specific bronchial hyperreactivity consistent with a reactive airways dysfunction syndrome.