Intravenous immunoglobulins and anti-idiotypic suppression of auto-immunity

This review summarizes the clinical use of intravenous immunoglobulins (IVIg) in autoimmune diseases and focuses on the mechanisms by which IVIg suppress autoimmune responses. Evidence is presented of a role of IVIg in modulating the regulatory function of the idiotypic network on the expression of...

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Bibliographic Details
Published in:	La revue de medecine interne Vol. 13; no. 2; p. 162
Main Authors:	Jobin, D, Kazatchkine, M
Format:	Journal Article
Language:	French
Published:	France 01-03-1992
Subjects:	Autoantibodies - immunology Autoimmune Diseases - therapy Humans Immunization, Passive Immunoglobulin Idiotypes - immunology Immunoglobulins - administration & dosage Injections, Intravenous
Online Access:	Get more information
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Summary:	This review summarizes the clinical use of intravenous immunoglobulins (IVIg) in autoimmune diseases and focuses on the mechanisms by which IVIg suppress autoimmune responses. Evidence is presented of a role of IVIg in modulating the regulatory function of the idiotypic network on the expression of the natural and pathological autoimmune repertoires.
ISSN:	0248-8663