Anticellular action of alpha-interferons of various origins

The results of the study of the anticellular effect of alpha-interferons of various origins (human, porcine, and bovine) on the growth of human lymphoblastoid cells (Namalva and J-96). Both homologous (human) and heterologous (porcine and bovine) leukocyte interferons produced a similar anticellular...

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Bibliographic Details
Published in:	Voprosy virusologiĭ no. 1; p. 32
Main Authors:	Pokidysheva, L N, Gulevich, N E, Lavrukhina, L A
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-01-1982
Subjects:	Animals Antineoplastic Agents - therapeutic use Burkitt Lymphoma - therapy Cattle Cells, Cultured Drug Evaluation, Preclinical Humans In Vitro Techniques Interferons - therapeutic use Leukemia, Myeloid - therapy Swine Time Factors
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Summary:	The results of the study of the anticellular effect of alpha-interferons of various origins (human, porcine, and bovine) on the growth of human lymphoblastoid cells (Namalva and J-96). Both homologous (human) and heterologous (porcine and bovine) leukocyte interferons produced a similar anticellular effect on the cells under study. All 3 types of interferon inhibited proliferation of lymphoblastoid cells. No such effect of these interferons on the control (diploid) cells was observed.
ISSN:	0507-4088