Results of the surgical treatment of Basedow's disease. Apropos of 30 cases

Thyroid function was evaluated after thyroidectomy in 30 cases of Graves' disease. 15 patients were euthyroid, 6 of them were TRH non responsive suggesting a risk of relapse. Indeed, the 3 proven cases of relapse were TRH non responsive before relapse and remained so after treatment. The severe...

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Bibliographic Details
Published in:	Annales d'endocrinologie Vol. 43; no. 3; p. 193
Main Authors:	Abdelmoumene, N, Maoui, R, El Okby, A, Benmiloud, M
Format:	Journal Article
Language:	French
Published:	France 01-05-1982
Subjects:	Adolescent Adult Algeria Carbimazole - adverse effects Female Follow-Up Studies Graves Disease - surgery Humans Hypothyroidism - etiology Iodine - deficiency Male Middle Aged Recurrence Thyroid Function Tests Thyroid Gland - pathology Thyroidectomy - adverse effects Thyrotropin - blood Thyrotropin-Releasing Hormone Algeria
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Summary:	Thyroid function was evaluated after thyroidectomy in 30 cases of Graves' disease. 15 patients were euthyroid, 6 of them were TRH non responsive suggesting a risk of relapse. Indeed, the 3 proven cases of relapse were TRH non responsive before relapse and remained so after treatment. The severe iodine deficiency in Algeria did not seem to increase the frequency of post-operative hypothyroidism. Neither did the duration of carbimazole therapy, the severity of thyroid lymphocytic infiltration or thyroid antibodies titer. Thyroid remnant size, although difficult to estimate, appears to be inversely related to post-operative TSH values.
ISSN:	0003-4266