Histocompatibility antigens (HLA) in children with lipoid nephrosis

Actual knowledge on the HLA relationship with the primary glomerulopathies, with particular reference to steroid - sensitive nephrosis of childhood, is surveyed. Occurrence of HLA B-8 and B-35 in this nephropathy has been investigated. The studies involved 47 patients aged between 3 and 15 years and...

Full description

Saved in:

Bibliographic Details
Published in:	Polski tygodnik lekarski (Warsaw, Poland : 1960) Vol. 47; no. 31-33; p. 671
Main Authors:	Zwolińska, D, Morawska, Z, Makulska, I, Dmochowska, D, Jaśniak, K, Morawski, A
Format:	Journal Article
Language:	Polish
Published:	Poland 07-08-1992
Subjects:	Adolescent Child Child, Preschool Female HLA-B35 Antigen - analysis HLA-B8 Antigen - analysis Humans Male Nephrosis, Lipoid - immunology Reference Values
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Actual knowledge on the HLA relationship with the primary glomerulopathies, with particular reference to steroid - sensitive nephrosis of childhood, is surveyed. Occurrence of HLA B-8 and B-35 in this nephropathy has been investigated. The studies involved 47 patients aged between 3 and 15 years and 117 healthy children from Lower Silesian region. It has been showed, that HLA B-8 is present more frequently in sick children, than in healthy controls. The situation is reverse in case of HLA B-35 antigen. However, the difference is statistically insignificant. A probability of the lipid nephrosis sensitivity to corticosteroids can not be predicted on the base of the presence of these HLA antigens.
ISSN:	0032-3756