Effect of the natriuretic factor obtained from arterial blood of dogs on cardio- and hemodynamics in experimental studies

The natriuretic factor, inhibiting Na-K-ATPase, exerts a stable positive inotropic and negative chronotropic effect as a result of its single administration in a dose stimulating the natriuretic activity of the kidneys. It also decreases the overall peripheral vascular resistance. The mean arterial...

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Bibliographic Details
Published in:Fiziologicheskii zhurnal Vol. 35; no. 2; p. 89
Main Authors: Konovchuk, V N, Mikhal'skiĭ, A V, Petriuk, A E, Ivanov, Iu N
Format: Journal Article
Language:Russian
Published: Ukraine 01-03-1989
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Summary:The natriuretic factor, inhibiting Na-K-ATPase, exerts a stable positive inotropic and negative chronotropic effect as a result of its single administration in a dose stimulating the natriuretic activity of the kidneys. It also decreases the overall peripheral vascular resistance. The mean arterial pressure slightly changes.
ISSN:0201-8489