Influence of digitoxin on isolated segments of lateral branches of human vena saphena (author's transl)

The effect of digitoxin on isolated segments of lateral branches of the human saphenous vein perfused in vitro with constant volumes is reported. Digitoxin, depending on concentraion, effected rise in perfusion pressure and intensification of reaction to norepinephrine. Some venous segments showed s...

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Bibliographic Details
Published in:	Arzneimittel-Forschung Vol. 26; no. 5; p. 910
Main Authors:	Salles Meirelles, R, Bailão, L A, Silva de Sá, M F, Mauad Filho, F, Franco Junior, J G, Filho, J D, Cherri, J
Format:	Journal Article
Language:	German
Published:	Germany 1976
Subjects:	Adult Digitoxin - pharmacology Humans Hypertrophy In Vitro Techniques Muscle Contraction - drug effects Muscle, Smooth - drug effects Norepinephrine - pharmacology Saphenous Vein - cytology Saphenous Vein - drug effects Vasomotor System - drug effects
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Summary:	The effect of digitoxin on isolated segments of lateral branches of the human saphenous vein perfused in vitro with constant volumes is reported. Digitoxin, depending on concentraion, effected rise in perfusion pressure and intensification of reaction to norepinephrine. Some venous segments showed spontaneous activity. The tests were supported by histological studies.
ISSN:	0004-4172