Kinetics studies on the renal transport of probenecid in vitro

1. The kinetic parameters of renal transport of probenecid have been assessed by studying the uptake of the drug in rabbit kidney tubules incubated in an electrolyte medium under various conditions. 2. The added compounds inhibited the uptake of probenecid both by kidney cortical slices and separate...

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Bibliographic Details

Published in:	Biochimica et biophysica acta Vol. 514; no. 2; p. 356
Main Authors:	Sheikh, M I, Maxild, J
Format:	Journal Article
Language:	English
Published:	Netherlands 19-12-1978
Subjects:	Animals Binding, Competitive Biological Transport, Active - drug effects Bromcresol Green - pharmacology Bromphenol Blue - pharmacology Female Kidney Tubules - metabolism Kinetics Male p-Aminohippuric Acid - pharmacology Phenolsulfonphthalein - pharmacology Probenecid - metabolism Rabbits
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