Role of the superior cervical sympathetic ganglion on regulating the amount of brain cell nuclear histones

The quantitative changes of histones and their fractions and of nonhistone proteins in nuclei of cerebral cells have been studied in normal animals and following removal of the right superior cervical ganglion. On the next day after sympathectomy the total amount of histones was shown to increase by...

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Bibliographic Details
Published in:	Voprosy biokhimii mozga Vol. 13; p. 138
Main Authors:	Mkheian, E E, Kocharian, K M
Format:	Journal Article
Language:	Russian
Published:	Armenia (Republic) 1978
Subjects:	Animals Brain Chemistry Cell Nucleus - analysis Female Ganglia, Sympathetic - physiology Histones - analysis Male Rats RNA - analysis Sympathectomy Transcription, Genetic
Online Access:	Get more information
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Summary:	The quantitative changes of histones and their fractions and of nonhistone proteins in nuclei of cerebral cells have been studied in normal animals and following removal of the right superior cervical ganglion. On the next day after sympathectomy the total amount of histones was shown to increase by 17% in nuclei of cells of the right hemisphere while in nuclei of cells of the left hemisphere an increase of 38% was observed 3 days after sympathectomy. Histone fractions rich in lysine were also found to increase. The amount of nonhistone proteins begins to decrease on the next day after sympathectomy and reaches 33% of control values by the third day.
ISSN:	0507-2972