Microarray analysis of Mycobacterium tuberculosis‐infected monocytes reveals IL26 as a new candidate gene for tuberculosis susceptibility

Summary Differences in the activity of monocytes/macrophages, important target cells of Mycobacterium tuberculosis, might influence tuberculosis progression. With the purpose of identifying candidate genes for tuberculosis susceptibility we infected monocytes from both healthy elderly individuals (a...

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Bibliographic Details
Published in:	Immunology Vol. 144; no. 2; pp. 291 - 301
Main Authors:	Guerra‐Laso, José M., Raposo‐García, Sara, García‐García, Silvia, Diez‐Tascón, Cristina, Rivero‐Lezcano, Octavio M.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01-02-2015 BlackWell Publishing Ltd
Subjects:	Adult Age Factors Aged Aged, 80 and over anti‐microbial activity Down-Regulation Female Genetic Predisposition to Disease Humans Interleukin-2 - blood Interleukins - blood Interleukins - genetics interleukin‐2 interleukin‐26 receptor Macrophages - immunology Male Middle Aged Monocytes - immunology Monocytes - microbiology monocytes/macrophages Mycobacterium tuberculosis - immunology Oligonucleotide Array Sequence Analysis Original Protein Array Analysis Receptors, Interleukin - biosynthesis Receptors, Interleukin - genetics RNA, Messenger - biosynthesis Tuberculosis, Pulmonary - genetics Young Adult interleukin-26 receptor interleukin-2 monocytes/macrophages anti-microbial activity
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