Dexamethasone-prepared Escherichia coli-induced disseminated intravascular coagulation. Animal model

We have developed a new model of disseminated intravascular coagulation in rats based on the induction of immunosuppression by prolonged high-dose dexamethasone treatment. Most models of disseminated intravascular coagulation are based on the generalized Shwartzman reaction, which is observed charac...

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Bibliographic Details

Published in:	Laboratory investigation Vol. 56; no. 5; p. 534
Main Authors:	Lopez-Garrido, J, Galera-Davidson, H, Ortega Medina, I, Martinez Navarro, A E, Leal Bermudez, J, Rodriguez Fernandez, A
Format:	Journal Article
Language:	English
Published:	United States 01-05-1987
Subjects:	Amoxicillin - pharmacology Animals Dexamethasone - pharmacology Disease Models, Animal Disseminated Intravascular Coagulation - etiology Disseminated Intravascular Coagulation - pathology Escherichia coli Infections - pathology Female Immunosuppression Kidney Glomerulus - pathology Lymphoid Tissue - pathology Mucins - pharmacology Rats Rats, Inbred Strains Thymus Gland - pathology
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