Tiagabine is associated with sustained attention during sleep restriction : Evidence for the value of slow-wave sleep enhancement?

To evaluate the impact of enhanced slow-wave sleep (SWS) on behavioral, psychological, and physiologic changes resulting from sleep restriction A double-blind, parallel-group, placebo-controlled design was used to compare tiagabine, 8 mg, (a SWS-enhancing drug) to placebo during 4 nights of sleep re...

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Bibliographic Details
Published in:	Sleep (New York, N.Y.) Vol. 29; no. 4; pp. 433 - 443
Main Authors:	WALSH, James K, RANDAZZO, Angela C, STONE, Kara, EISENSTEIN, Rhody, FEREN, Stephen D, KAJY, Susan, DICKEY, Pam, ROEHRS, Timothy, ROTH, Thomas, SCHWEITZER, Paula K
Format:	Journal Article
Language:	English
Published:	Rochester, MN American Academy of Sleep Medicine 01-04-2006
Subjects:	Activity levels. Psychomotricity Adult Arousal - drug effects Attention - drug effects Biological and medical sciences Double-Blind Method Electroencephalography Female Fundamental and applied biological sciences. Psychology GABA Agonists - administration & dosage GABA Agonists - pharmacology Humans Male Neuropsychological Tests Nipecotic Acids - administration & dosage Nipecotic Acids - pharmacology Polysomnography Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychomotor Performance - drug effects Reaction Time - drug effects Sleep - drug effects Sleep Deprivation - drug therapy Sleep Deprivation - physiopathology Sleep Deprivation - psychology Vigilance. Attention. Sleep Human Reuptake inhibitor Polysomnography Slow wave sleep Tiagabine Electrodiagnosis Placebo GABA Neurotransmitter Double blind study Value Sustained attention Sleep wake cycle
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