Lack of evidence of nosocomial cross-infection by Burkholderia cepacia among Danish cystic fibrosis patients

• Published in: European journal of clinical microbiology & infectious diseases Vol. 15; no. 9; pp. 755 - 758
• Main Authors: RYLEY, H. C, OJENIYI, B, HØIBY, N, WEEKS, J
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01-09-1996
• Subjects: Biological and medical sciences; Burkholderia cepacia - isolation & purification; Burkholderia Infections - complications; Burkholderia Infections - diagnosis; Burkholderia Infections - epidemiology; Cross Infection - complications; Cross Infection - diagnosis; Cross Infection - epidemiology; Cystic Fibrosis - complications; Cystic Fibrosis - microbiology; Denmark - epidemiology; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Incidence; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Medical sciences; Other diseases. Semiology; Polymerase Chain Reaction; Denmark; Europe; Human; Nosocomial infection; Typing; Respiratory disease; Metabolic diseases; Cystic fibrosis; Epidemiology; Genetic disease; Infection; Microbiological investigation; Burkholderia cepacia; Bacteriosis; Digestive diseases; Bacteria; Complication; Pancreatic disease
• ISSN: 0934-9723; 1435-4373
• DOI: 10.1007/BF01691967

Burkholderia cepacia isolates from nine of the ten Danish cystic fibrosis (CF) patients known between 1975 and the present day to carry this organism were investigated. Eight distinct genotypes were found with polymerase chain reaction ribotyping and pulsed-field gel electrophoresis. The results indicate that there is little patient-to-patient cross-infection with Burkholderia cepacia within the Danish CF population, even though the majority of patients attend the same CF clinic on a regular basis.