The epithelial-mesenchymal transition (EMT) and colorectal cancer progression

During embryonic development, epithelial cells must escape the structural constraints imposed by tissue architecture and adopt a phenotype more amenable to cell movement, a process known as the epithelial-mesenchymal transition (EMT). The progression of carcinomas to invasive and metastatic disease...

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Bibliographic Details

Published in:	Cancer biology & therapy Vol. 4; no. 4; pp. 365 - 370
Main Authors:	Bates, Richard C, Mercurio, Arthur M
Format:	Journal Article
Language:	English
Published:	United States 01-04-2005
Subjects:	Animals Antigens, Neoplasm - metabolism Biomarkers, Tumor Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Disease Progression Epithelium - metabolism Epithelium - pathology Humans Integrins - metabolism Mesoderm - metabolism Mesoderm - pathology Transforming Growth Factor beta - metabolism Tumor Necrosis Factor-alpha - metabolism Vascular Endothelial Growth Factor A - metabolism
Online Access:	Get full text
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