Neuropsychological evaluation of neurologically asymptomatic HIV-infected children

• Published in: Brain and cognition Vol. 43; no. 1-3; pp. 49 - 52
• Main Authors: Bisiacchi, P S, Suppiej, A, Laverda, A
• Format: Journal Article
• Language: English
• Published: United States 01-06-2000
• Subjects: Adolescent; AIDS/HIV; Child; Cognition Disorders - diagnosis; Cognition Disorders - etiology; Female; HIV Seropositivity - complications; Humans; Male; Neuropsychological Tests; Severity of Illness Index
• ISSN: 0278-2626

Forty-two children born to HIV positive mothers (29 infected at different stages of the disease, according to the Disease Control Classification Centers, and 13 noninfected) underwent evaluation using a battery of neuropsychological tests. Executive function impairments were present in all infected children, whereas memory and visuo-prassic deficits were evident only in those with full-blown AIDS. Language abilities and overall intelligence were spared. Performance of seroreverters was in the normal range. These findings suggest that even in neurologically asymptomatic children, neuropsychological evaluation can identify early impairment of specific cognitive functions. The findings are discussed in the light of the prognostic power of neuropsychological assessment for early signs of HIV neurological involvement.