Internalization and recycling of delta-opioid receptor are dependent on a phosphorylation-dephosphorylation mechanism

Internalization, recycling, and resensitization of the human delta-opioid receptor (hDOR) were studied in the neuroblastoma cell line SK-N-BE, endogenously expressing this receptor. Conventional and confocal fluorescence microscopy observations, corroborated by Scatchard analysis, indicated that aft...

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Bibliographic Details
Published in:	The Journal of pharmacology and experimental therapeutics Vol. 293; no. 1; p. 237
Main Authors:	Hasbi, A, Allouche, S, Sichel, F, Stanasila, L, Massotte, D, Landemore, G, Polastron, J, Jauzac, P
Format:	Journal Article
Language:	English
Published:	United States 01-04-2000
Subjects:	Brain Neoplasms - metabolism Concanavalin A - pharmacology Cyclic AMP - metabolism Diprenorphine - metabolism Heparin - pharmacology Humans Hypertonic Solutions Immunohistochemistry Microscopy, Confocal Narcotic Antagonists - metabolism Neuroblastoma - metabolism Ovalbumin - pharmacology Phosphorylation Radioligand Assay Receptors, Opioid, delta - agonists Receptors, Opioid, delta - immunology Receptors, Opioid, delta - metabolism Sucrose - pharmacology Tumor Cells, Cultured
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