The in vivo binding site for oncoprotein c-Myc in the promoter for Epstein-Barr virus (EBV) encoding RNA (EBER) 1 suggests a specific role for EBV in lymphomagenesis

Epstein-Barr virus (EBV) was isolated in the 1960s from the African childhood tumor, Burkitt's Lymphoma (BL), characterized by the translocation of the c-myc gene into one of the immunoglobulin loci. Due to the extreme discrepancy between the widespread dissemination of EBV infection and the ov...

Full description

Saved in:

Bibliographic Details
Published in:	Medical science monitor Vol. 9; no. 1; p. HY1
Main Authors:	Niller, Hans H, Salamon, Daniel, Ilg, Karin, Koroknai, Anita, Banati, Ferenc, Bauml, Gerald, Rucker, Ovidiu, Schwarzmann, Fritz, Wolf, Hans, Minarovits, Janos
Format:	Journal Article
Language:	English
Published:	United States 01-01-2003
Subjects:	Binding Sites Cell Line, Transformed Chromatin - metabolism Dimethyl Sulfoxide - pharmacology Genes, myc - genetics Herpesvirus 4, Human - metabolism Hodgkin Disease - genetics Humans Luciferases - metabolism Lymphoma - etiology Lymphoma - virology Lymphoma, Non-Hodgkin - genetics Models, Genetic Phenotype Plasmids - metabolism Precipitin Tests Promoter Regions, Genetic Protein Binding Proto-Oncogene Proteins c-myc - chemistry Proto-Oncogene Proteins c-myc - metabolism RNA, Viral - genetics Transfection Tumor Cells, Cultured
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!