Complications associated with bovine corneal endothelial cell-lined homografts in the cat

Cultured bovine corneal endothelial cells were subcultured onto feline corneas from which the native endothelium had been mechanically removed, and transplanted into cats via penetrating keratoplasty. Although the transplants remained thin and clear in the immediate postoperative period, correlative...

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Bibliographic Details
Published in:	Investigative ophthalmology & visual science Vol. 22; no. 1; pp. 73 - 90
Main Authors:	Bahn, C F, MacCallum, D K, Lillie, J H, Meyer, R F, Martonyi, C L
Format:	Journal Article
Language:	English
Published:	United States 01-01-1982
Subjects:	Animals Cats Cattle Cells, Cultured Cornea - cytology Corneal Transplantation Endothelium - cytology Graft Rejection Microscopy, Electron, Scanning Transplantation, Autologous Transplantation, Heterologous Transplantation, Homologous
Online Access:	Get full text
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Summary:	Cultured bovine corneal endothelial cells were subcultured onto feline corneas from which the native endothelium had been mechanically removed, and transplanted into cats via penetrating keratoplasty. Although the transplants remained thin and clear in the immediate postoperative period, correlative clinical and morphologic analysis disclosed evidence of a host response directed against the heterologous endothelium by the ninth postoperative day. Eyes with rotational autografts or transplanted homografts did not disclose evidence of a similar host response.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0146-0404