Alterations in renal function in experimental congestive heart failure

The delicate interplay between vasoconstrictors and vasodilators preserves glomerular filtration in CHF despite marked hypoperfusion. Activation of vasoconstrictive systems seems to depend on the severity and the chronicity of the disease. The importance of renin-angiotensin, sympathetic nerves, vas...

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Bibliographic Details
Published in:	Seminars in nephrology Vol. 14; no. 5; p. 401
Main Authors:	Awazu, M, Ichikawa, I
Format:	Journal Article
Language:	English
Published:	United States 01-09-1994
Subjects:	Animals Atrial Natriuretic Factor - physiology Dogs Dopamine - physiology Endothelins - physiology Heart Failure - physiopathology Kidney - physiopathology Natriuretic Peptide, Brain Nerve Tissue Proteins - physiology Nitric Oxide - physiology Prostaglandins - physiology Rats Renin-Angiotensin System - physiology Sympathetic Nervous System - physiology Vasopressins - physiology Water-Electrolyte Imbalance - physiopathology
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Summary:	The delicate interplay between vasoconstrictors and vasodilators preserves glomerular filtration in CHF despite marked hypoperfusion. Activation of vasoconstrictive systems seems to depend on the severity and the chronicity of the disease. The importance of renin-angiotensin, sympathetic nerves, vasopressin and counterregulatory ANP, and prostaglandins in CHF has been elucidated. Possible roles of newly identified substances, such as endothelin and EDRF, deserve investigation.
ISSN:	0270-9295