The influence of age on the distribution and activity of histamine receptors in the rat uterus

In immature rat uterus histamine (10(-6) mol.l-1) potentiates by 25%, the carbachol (2 x 10(-6) mol.l-1) induced uterine contractions. This potentiation is abolished by mepyramine (6 x 10(-9) mol.l-1), an H1-receptor antagonist. Higher concentrations of histamine, up to 10(-4) mol.l-1, did not exert...

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Bibliographic Details

Published in:	Methods and findings in experimental and clinical pharmacology Vol. 6; no. 2; p. 79
Main Authors:	Paradelis, A G, Triantaphyllidis, C J, Fidani, V, Crassaris, L G, Papadopoulos, A G, Stavrakis, A O
Format:	Journal Article
Language:	English
Published:	Spain 01-02-1984
Subjects:	Aging Animals Carbachol - pharmacology Cimetidine - pharmacology Electric Stimulation Female Histamine - pharmacology Pyrilamine - pharmacology Rats Rats, Inbred Strains Receptors, Histamine - metabolism Receptors, Histamine H1 - metabolism Receptors, Histamine H2 - metabolism Uterine Contraction - drug effects Uterus - metabolism
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