Theophylline half-life in infants and young children

Pharmacokinetics of theophylline elimination were studied in a 54-child population. Subjects' ages ranged from three months to six years. The mean half life was 4.92 hours, with S.D. +/- 1.88 hours. This is at variance with previous reports. Ages and half lives were compared and there were no c...

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Bibliographic Details
Published in:	Annals of allergy Vol. 40; no. 5; p. 303
Main Authors:	Kadlec, G J, Ha, L T, Jarboe, C H, Richards, D, Karibo, J M
Format:	Journal Article
Language:	English
Published:	United States 01-05-1978
Subjects:	Child Child, Preschool Dose-Response Relationship, Drug Half-Life Humans Infant Theophylline - pharmacology
Online Access:	Get more information
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Summary:	Pharmacokinetics of theophylline elimination were studied in a 54-child population. Subjects' ages ranged from three months to six years. The mean half life was 4.92 hours, with S.D. +/- 1.88 hours. This is at variance with previous reports. Ages and half lives were compared and there were no correlations in this young age group.
ISSN:	0003-4738