Generation of HER-2/neu-specific cytotoxic neutrophils in vivo: Efficient arming of neutrophils by combined administration of granulocyte colony-stimulating factor and Fc gamma receptor I bispecific antibodies

Abs are able to induce inflammatory antitumor responses by recruiting IgG Fc receptor (Fc gamma R)-bearing cytotoxic effector cells. We recently described the capacity of the high affinity Fc gamma RI (CD64) to trigger cytotoxic activity of neutrophils (PMN) during granulocyte CSF (G-CSF) treatment....

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Bibliographic Details

Published in:	The Journal of immunology (1950) Vol. 159; no. 11; pp. 5629 - 5639
Main Authors:	Heijnen, IAFM, Rijks, LJM, Schiel, A, Stockmeyer, B, van Ojik, HH, Dechant, M, Valerius, T, Keler, T, Tutt, AL, Glennie, MJ, van Royen, EA, Capel, PJA, van de Winkel, JGJ
Format:	Journal Article
Language:	English
Published:	01-12-1997
Online Access:	Get full text
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