Iodine overload and severe hypothyroidism in two neonates

Iodine overload frequently leads to transient hyperthyrotropinemia or hypothyroidism, and rarely to hyperthyroidism in neonates. Iodine exposure can be prenatal, perinatal or postnatal. Herein we report two newborn infants who developed severe hypothyroidism due to iodine overload. The overloading w...

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Bibliographic Details
Published in:	Journal of clinical research in pediatric endocrinology Vol. 1; no. 6; pp. 275 - 277
Main Authors:	Kurtoğlu, Selim, Akın, Leyla, Akın, Mustafa Ali, Çoban, Dilek
Format:	Journal Article
Language:	English
Published:	Turkey Galenos Publishing 01-12-2009
Subjects:	Case Reports Female Humans Hypothyroidism - chemically induced Infant, Newborn Iodine - poisoning Male Maternal Exposure - adverse effects Milk, Human - chemistry hypothyroidism Neonate Iodine overload
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Summary:	Iodine overload frequently leads to transient hyperthyrotropinemia or hypothyroidism, and rarely to hyperthyroidism in neonates. Iodine exposure can be prenatal, perinatal or postnatal. Herein we report two newborn infants who developed severe hypothyroidism due to iodine overload. The overloading was caused by excessive use of an iodinated antiseptic for umbilical care in the first case, and as a result of maternal exposure and through breast milk with a high iodine level in the second case. Presenting the two cases, we wanted to draw attention to these preventable causes of hypothyroidism in infants.
ISSN:	1308-5727 1308-5735
DOI:	10.4274/jcrpe.v1i6.275