Structure of the DNA interstrand cross-link of 4,5',8-trimethylpsoralen

4,5',8-Trimethylpsoralen (TMP) cross-links a 5' TpA or a 5' ApT site by photoreacting with one thymine moiety in each DNA strand. We are interested in whether psoralen interstrand cross-links all share one structure or whether there are significant differences. In this paper, we emplo...

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Bibliographic Details
Published in:	Biochemistry (Easton) Vol. 31; no. 29; pp. 6774 - 6783
Main Authors:	KUMARESAN, K. R, MUTHUKUMAR RAMASWAMY, YEUNG, A. T
Format:	Journal Article
Language:	English
Published:	Washington, DC American Chemical Society 28-07-1992
Subjects:	Analytical, structural and metabolic biochemistry Base Composition Base Sequence Biological and medical sciences Cross-Linking Reagents - chemistry DNA - chemistry Dna, deoxyribonucleoproteins Electrophoresis, Polyacrylamide Gel Fundamental and applied biological sciences. Psychology Hydrogen Bonding Models, Structural Molecular Sequence Data Nucleic Acid Conformation Nucleic acids Oligodeoxyribonucleotides - chemical synthesis Oligodeoxyribonucleotides - chemistry Structure-Activity Relationship Thymine Trioxsalen - chemistry Crosslink agent Stability Base pairing DNA Molecular adduct Psoralen derivatives
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