Case report: primary infection by human herpesvirus 6 variant a with the onset of myelitis

A case of primary infection by human herpesvirus 6 (HHV-6) variant A in a 54-year-old woman, which occurred at the same time as the onset of encephalomyelitis, is reported. The correlation between the two events is discussed. It is speculated that, during the early phase of the infection, the HHV-6...

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Bibliographic Details
Published in:	Herpes Vol. 13; no. 3; p. 72
Main Authors:	Portolani, Marinella, Pecorari, Monica, Gennari, William, Beretti, Francesca, Sabbatini, Anna Maria Teresa, Casolari, Chiara, Rumpianesi, Fabio, Cermelli, Claudio, Sintini, Michele, Mori, Fernanda
Format:	Journal Article
Language:	English
Published:	England 01-11-2006
Subjects:	Cervical Vertebrae - diagnostic imaging DNA, Viral - blood DNA, Viral - cerebrospinal fluid Encephalomyelitis - diagnostic imaging Encephalomyelitis - virology Female Genetic Variation Herpesvirus 6, Human - classification Herpesvirus 6, Human - genetics Herpesvirus 6, Human - isolation & purification Humans Middle Aged Radiography Roseolovirus Infections - complications Roseolovirus Infections - diagnostic imaging Roseolovirus Infections - virology
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Summary:	A case of primary infection by human herpesvirus 6 (HHV-6) variant A in a 54-year-old woman, which occurred at the same time as the onset of encephalomyelitis, is reported. The correlation between the two events is discussed. It is speculated that, during the early phase of the infection, the HHV-6 spread to the central nervous system and triggered a pathogenic process that initially developed without symptoms. When the neurological disorders appeared, HHV-6 had already established a latent state: only the virus carried by infected blood cells was detected in the cerebrospinal fluid.
ISSN:	0969-7667