Murine Membranous Nephropathy: Immunization with alpha 3(IV) Collagen Fragment Induces Subepithelial Immune Complexes and Fc gamma R-Independent Nephrotic Syndrome
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and a significant cause of end-stage renal disease, yet current therapies are nonspecific, toxic, and often ineffective. The development of novel targeted therapies requires a detailed understanding of the pathogenic mech...
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Published in: | The Journal of immunology (1950) Vol. 188; no. 7; pp. 3268 - 3277 |
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Main Authors: | , , , , , , , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
01-04-2012
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Online Access: | Get full text |
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