Murine Membranous Nephropathy: Immunization with alpha 3(IV) Collagen Fragment Induces Subepithelial Immune Complexes and Fc gamma R-Independent Nephrotic Syndrome

Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults and a significant cause of end-stage renal disease, yet current therapies are nonspecific, toxic, and often ineffective. The development of novel targeted therapies requires a detailed understanding of the pathogenic mech...

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Bibliographic Details
Published in:The Journal of immunology (1950) Vol. 188; no. 7; pp. 3268 - 3277
Main Authors: Zhang, Jun-Jun, Malekpour, Mahdi, Luo, Wentian, Ge, Linna, Olaru, Florina, Wang, Xu-Ping, Bah, Maimouna, Sado, Yoshikazu, Heidet, Laurence, Kleinau, Sandra, Fogo, Agnes B, Borza, Dorin-Bogdan
Format: Journal Article
Language:English
Published: 01-04-2012
Online Access:Get full text
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