Controversies in COX-2 selective inhibition

• Published in: Journal of rheumatology Vol. 29; no. 7; pp. 1501 - 1510
• Main Authors: SIMON, Lee S, SMOLEN, Josef S, DOUGADOS, Maxime, DUBOIS, Raymond N, FITZGERALD, Garret A, FRISHMAN, W, GARCIA RODRIGUEZ, Luis A, HOCHBERG, Marc C, KALDEN, Joachim R, LAINE, Loren, LANGMAN, Michael J. S, PRESCOTT, Stephen M, ABRAMSON, Steven B, VAN DE PUTTE, Leo B. A, WHELTON, Andrew, WHITE, William B, WILLIAMS, Gordon H, APPEL, Gerald, BOMBARDIER, Claire, BRATER, D. Craig, BREEDVELD, Ferdinand C, BRUNE, Kay, BURMESTER, Gerd R, CROFFORD, Leslie J
• Format: Journal Article
• Language: English
• Published: Toronto, ON Journal of Rheumatology Publishing 01-07-2002
• Subjects: Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use; Arthritis, Rheumatoid - diagnosis; Arthritis, Rheumatoid - drug therapy; Aspirin - adverse effects; Aspirin - therapeutic use; Biological and medical sciences; Bones, joints and connective tissue. Antiinflammatory agents; Cyclooxygenase Inhibitors - adverse effects; Cyclooxygenase Inhibitors - therapeutic use; Dose-Response Relationship, Drug; Drug Interactions; Female; Gastrointestinal Diseases - chemically induced; Gastrointestinal Diseases - physiopathology; Humans; Male; Maximum Tolerated Dose; Medical sciences; Pharmacology. Drug treatments; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Human; Prostaglandin-endoperoxide synthase; Rofecoxib; Duodenal disease; Enzyme; Isozyme; Toxicity; Treatment efficiency; Rheumatology; Celecoxib; Chemotherapy; Gastroduodenal; Treatment; Digestive diseases; Critical study; Inhibitor; Oxidoreductases; Mechanism of action; Gastric disease
• ISSN: 0315-162X; 1499-2752