Neurological disorders in Nigerian children with homozygous sickle cell anaemia

The pattern of associated Central Nervous System (CNS) disorders in children with homozygous sickle cell anaemia was studied over a 12-month period at the University of Nigeria Teaching Hospital (UNTH), Enugu. The relative incidence of associated neurological disorders was 1.3%, and the major variet...

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Bibliographic Details
Published in:	East African medical journal Vol. 66; no. 10; p. 653
Main Authors:	Izuora, G I, Kaine, W N, Emodi, I
Format:	Journal Article
Language:	English
Published:	Kenya 01-10-1989
Subjects:	Adolescent Anemia, Sickle Cell - complications Central Nervous System Diseases - epidemiology Central Nervous System Diseases - etiology Child Child, Preschool Female Humans Incidence Infant Infant, Newborn Male Nigeria - epidemiology Nigeria
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Summary:	The pattern of associated Central Nervous System (CNS) disorders in children with homozygous sickle cell anaemia was studied over a 12-month period at the University of Nigeria Teaching Hospital (UNTH), Enugu. The relative incidence of associated neurological disorders was 1.3%, and the major varieties were cerebrovascular accidents (57.5%), meningitis (22.5%) and recurrent convulsions (10%). Intellectual impairment did not feature as a separate entity, but was observed in 27.5% of children with CNS complications. Although recurrent strokes were not frequently encountered, the hypertransfusion therapy was not practised because of relative scarcity of blood donors.
ISSN:	0012-835X