Non Optical Semi-Conductor Next Generation Sequencing of the Main Cardiac QT-Interval Duration Genes in Pooled DNA Samples

DNA variants at the genes encoding cardiac channels have been associated with inherited arrhythmias and the QT interval in the general population. Next generation sequencing technologies would be of special interest to uncover the genetic variation at these genes. The amplification and sequencing of...

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Bibliographic Details
Published in:	Journal of cardiovascular translational research Vol. 7; no. 1; pp. 133 - 137
Main Authors:	Gómez, Juan, Reguero, Julian R., Morís, César, Alvarez, Victoria, Coto, Eliecer
Format:	Journal Article
Language:	English
Published:	Boston Springer US 01-02-2014
Subjects:	Biomedical Engineering and Bioengineering Biomedicine Cardiology Genetic Predisposition to Disease Genetic Testing - methods Genetic Variation Heart Rate - genetics High-Throughput Nucleotide Sequencing - methods Human Genetics Humans Long QT Syndrome - diagnosis Long QT Syndrome - genetics Long QT Syndrome - physiopathology Medicine Medicine & Public Health Multiplex Polymerase Chain Reaction NAV1.5 Voltage-Gated Sodium Channel - genetics Phenotype Potassium Channels, Voltage-Gated - genetics Predictive Value of Tests Reproducibility of Results DNA pools Cardiac arrhythmia genes Next generation sequencing Ion torrent sequencing
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