Reference ranges for lymphocyte subsets in a defined Malaysian population

The aim of this study was to establish the lymphocyte subset reference ranges in a defined Malaysian population as well as to determine inter-racial differences for these values. Normal blood obtained from 152 subjects (55.9% Malay, 26.3% Chinese and 17.7% Indian) was immunophenotyped. Results obtai...

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Bibliographic Details
Published in:	Singapore medical journal Vol. 36; no. 3; p. 288
Main Authors:	Dhaliwal, J S, Balasubramaniam, T, Quek, C K, Gill, H K, Nasuruddin, B A
Format:	Journal Article
Language:	English
Published:	Singapore 01-06-1995
Subjects:	Adolescent Adult Asian Continental Ancestry Group China - ethnology European Continental Ancestry Group Female Humans Immunophenotyping India - ethnology Lymphocyte Subsets - chemistry Malaysia Male Middle Aged Reference Values China Malaysia India
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Summary:	The aim of this study was to establish the lymphocyte subset reference ranges in a defined Malaysian population as well as to determine inter-racial differences for these values. Normal blood obtained from 152 subjects (55.9% Malay, 26.3% Chinese and 17.7% Indian) was immunophenotyped. Results obtained (expressed as mean +/- SD %), absolute count (x 10(6) cells/mm3) were as follows: CD3:66.5 +/- 8.6%, 2,066; CD4:33.2 +/- 8.5%, 1,028; CD831.6 +/- 8.9%, 982; CD19:12.0 +/- 0%, 5,374, and CD56+CD16:20.9 +/- 9%, 1,638. There were no significant differences between the percent lymphocyte subsets of the three racial groups. However, the absolute number of CD4 cells and CD19 cells in Chinese was significantly lower (p < 0.05) compared to the Indian and the Indian and Malay groups respectively. Comparison of our results with other reports showed that the percentage of Natural Killer cells in this population is higher than that reported for Caucasian population.
ISSN:	0037-5675