Regulation of ocular mucin secretion by P2Y2 nucleotide receptors in rabbit and human conjunctiva

The effects of adenine analogues on secretion of high molecular weight, mucin-like glycoproteins (mucins) by conjunctival goblet cells were investigated using isolated rabbit and human conjunctiva. Mucin secretion was assayed using a quantitative dot-blot assay of Helix pomatia agglutinin-horseradis...

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Bibliographic Details
Published in:	Experimental eye research Vol. 67; no. 3; pp. 341 - 346
Main Authors:	JUMBLATT, J. E, JUMBLATT, M. M
Format:	Journal Article
Language:	English
Published:	London Elsevier 01-09-1998
Subjects:	Adenosine Diphosphate - pharmacology Adenosine Monophosphate - pharmacology Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - pharmacology Aged Aged, 80 and over Animals Biological and medical sciences Conjunctiva - cytology Conjunctiva - drug effects Conjunctiva - metabolism Electrophoresis, Polyacrylamide Gel Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Goblet Cells - drug effects Goblet Cells - secretion Humans Immunoblotting Inositol 1,4,5-Trisphosphate - pharmacology Middle Aged Mucins - secretion Rabbits Receptors, Purinergic P2 - metabolism Receptors, Purinergic P2Y2 Stimulation, Chemical Thionucleotides - pharmacology Uridine Triphosphate - pharmacology Vertebrates: nervous system and sense organs Human Purine nucleotide Secretion Rabbit P2 Purinergic receptor Lagomorpha Conjunctiva Eye Visual system Vertebrata Mammalia Mucin Pyrimidine nucleotide
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