The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA

Lipoprotein-associated phospholipase A₂ (Lp-PLA₂) is a risk factor of cardiovascular disease. Plasma Lp-PLA₂ is mainly associated with apolipoprotein (apo)B-containing lipoproteins, primarily with low density lipoproteins (LDLs). Importantly, only a proportion of circulating lipoproteins contain Lp-...

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Bibliographic Details
Published in:	Journal of lipid research Vol. 54; no. 12; pp. 3394 - 3402
Main Authors:	Tellis, Constantinos C, Moutzouri, Eliza, Elisaf, Moses, Wolfert, Robert L, Tselepis, Alexandros D
Format:	Journal Article
Language:	English
Published:	United States 01-12-2013
Subjects:	1-Alkyl-2-acetylglycerophosphocholine Esterase - blood Adult Aged Apolipoproteins B - blood Calibration Female Humans Hypercholesterolemia - blood Hypercholesterolemia - drug therapy Hypercholesterolemia - enzymology Male Middle Aged Simvastatin - therapeutic use Young Adult simvastatin low density lipoprotein lipoprotein-associated phospholipase A2-bound apolipoprotein B hypercholesterolemia
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