Sleep disturbances in Parkinson's disease: characteristics, evaluation and therapeutic approaches

• Published in: Orvosi hetilap Vol. 156; no. 27; p. 1091
• Main Authors: Faludi, Béla, Janszky, József, Komoly, Sámuel, Kovács, Norbert
• Format: Journal Article
• Language: Hungarian
• Published: Hungary 05-07-2015
• Subjects: Antiparkinson Agents - administration & dosage; Antiparkinson Agents - adverse effects; Antiparkinson Agents - therapeutic use; Brain Stem - physiopathology; Circadian Rhythm; Dopamine Agents - administration & dosage; Dopamine Agents - adverse effects; Dopamine Agents - therapeutic use; Humans; Parkinson Disease - complications; Parkinson Disease - drug therapy; Parkinson Disease - metabolism; Parkinson Disease - physiopathology; Parkinson Disease - prevention & control; Quality of Life; REM Sleep Behavior Disorder - etiology; REM Sleep Behavior Disorder - therapy; Restless Legs Syndrome - etiology; Restless Legs Syndrome - therapy; Self Report; Sleep; Sleep Apnea, Obstructive - etiology; Sleep Apnea, Obstructive - therapy; Sleep Deprivation; Sleep Initiation and Maintenance Disorders - etiology; Sleep Initiation and Maintenance Disorders - therapy; Sleep Stages; Sleep Wake Disorders - diagnosis; Sleep Wake Disorders - etiology; Sleep Wake Disorders - physiopathology; Sleep Wake Disorders - prevention & control; Sleep Wake Disorders - therapy; Surveys and Questionnaires; sleep apnoe; restless legs syndrome; therapy; alvási apnoe; nyugtalan láb szindróma; REM behaviour disorder; REM-magatartászavar; insomnia; sleep disturbances; terápia; Parkinson-kór; alvászavar; Parkinson’s disease
• ISSN: 0030-6002
• DOI: 10.1556/650.2015.30191

Parkinson's disease is a well known representent of the movement disorder group of neurological disorders. The diagnosis of Parkinson's disease is based on specific symptoms and signs of movement abnormalities. In addition to classic motor symptoms, Parkinson's disease has characteristic non-motor features, and some of these emerges the classic signs.
The authors discuss characteristics and therapeutic interventions in Parkinson's disease related sleep disturbances.
The authors reviewed and summarised literature data on sleep disorders in Parkinson's disease published in the PubMed database up to January 2015.
Sleep problems are important non-motor complains (insomnia, hypersomnia, REM behaviour disorder, sleep apnea and restless legs syndrome). The neurodegenerative process of the brain-stem, the effect of symptoms of Parkinson's disease on sleep and concomitant sleep disorders constitute the background of the patient's complains.
Appropriate diagnosis and therapy of the consequential or concomitant sleep disorders in Parkinson's disease will help to improve the patient's quality of life.