Cutaneous mastocytosis: A case report

• Published in: Revista chilena de pediatria Vol. 87; no. 3; p. 204
• Main Authors: Zegpi-Trueba, María Soledad, Hasbún-Acuña, Paula, Berroeta-Mauriziano, Daniela
• Format: Journal Article
• Language: Spanish
• Published: Chile 01-05-2016
• Subjects: Biopsy; Female; Histamine H1 Antagonists - therapeutic use; Humans; Infant; Mastocytosis, Cutaneous - diagnosis; Mastocytosis, Cutaneous - pathology; Mastocytosis, Cutaneous - therapy; Prognosis; Urticaria Pigmentosa - diagnosis; Urticaria Pigmentosa - pathology; Urticaria Pigmentosa - therapy; Urticaria pigmentosa; Mastocytosis; Mastocitosis; Mastocytoma; Mastocitoma; Histamine H1 antagonist; Antagonistas de los receptores de histamina H1
• ISSN: 0717-6228
• DOI: 10.1016/j.rchipe.2015.09.004

Mastocytosis represents a group of diseases characterised by an excesive accumulation of mastocytes in one or multiple tissues. It can affect only the skin, or have a systemic involvement. It has a low prevalence, and the prognosis is benign in children.
To report a case of urticaria pigmentosa as a subtype of cutaneous mastocytosis, and present a literature review focused on clinical findings, diagnosis and initial basic management.
A child of six months of age presenting with multiple blemishes and light brown papules located on the trunk, arms and legs. The symptoms were compatible with urticaria pigmentosa, and was confirmed by biopsy. Tests to rule out systemic involvement were requested. The patient was treated with general measures, education, and antihistamines, with favourable results.
Cutaneous mastocytosis is a rare disease with a good prognosis. In childhood general measures and education are usually enough to obtain favourable results. Histamine H1 antagonists are the first line drug treatment.