Comparison of subthalamic nucleus planning coordinates in 1Tesla and 3Tesla MRI for deep brain stimulation targeting

• Published in: Ideggyógyászati szemle Vol. 71; no. 11-12; pp. 405 - 410
• Main Authors: Juhász, Annamária, Kovács, Norbert, Perlaki, Gábor, Büki, András, Komoly, Sámuel, Kövér, Ferenc, Balás, István
• Format: Journal Article
• Language: Hungarian
• Published: Hungary 30-11-2018
• Subjects: Deep Brain Stimulation - methods; Electrodes, Implanted; Humans; Magnetic Resonance Imaging - methods; Parkinson Disease - therapy; Stereotaxic Techniques; Subthalamic Nucleus - surgery; Treatment Outcome; 3 Tesla; 1 Tesla; comparison; planning coordinates; subthalamic nucleus; deep brain stimulation
• ISSN: 0019-1442
• DOI: 10.18071/isz.71.0405

Deep brain stimulation (DBS) involves placing electrodes within specific deep brain nuclei. For movement disorders the most common indications are tremors, Parkinsons disease and dystonias. Surgeons mostly employ MR imaging for preoperative target selection. MR field geometrical distortion may contribute to target-selection error in the MR scan which can contribute to error in electrode placement.
In this paper we compared the STN target planning coordinates in six parkinsonian DBS patients. Each patient underwent target planning in 1T and 3T MRI. We statistically compared and analysed the target-, and the fiducial coordinates in two different magnetic fileds.
The target coordinates showed no significant differences (Mann-Whitney test, p > 0.05), however we found significant difference in fiducial coordinates (p < 0.01), in 3T MRI it was more pronounced (mean ± SD: 0.8 ± 0.3 mm) comparing to 1T (mean ± SD: 0.4 ± 0.2 mm).
Preliminary results showed no significant differences in planning of target coordinates comparing 1T to 3T magnetic fields.