Mucinous tubular and spindle cell renal cell carcinoma: two novel cases and a literature review.

• Published in: Archivos españoles de urología Vol. 75; no. 1; p. 19
• Main Authors: Pérez-González, Sonia, Del Rosario-Rodríguez, Virginia, Feltes-Ochoa, Javier Amalio, Gimeno-Aranguez, Margarita, Alcojor-Ballesteros, Ignacio, Carrero-López, Víctor Manuel
• Format: Journal Article
• Language: Spanish
• Published: Spain 01-01-2022
• Subjects: Adenocarcinoma, Mucinous - diagnosis; Adenocarcinoma, Mucinous - surgery; Carcinoma, Renal Cell - diagnosis; Female; Humans; Kidney - pathology; Kidney Neoplasms - pathology; Male; Middle Aged; Nephrectomy; Immunohistochemistry; Pathology; Carcinoma renal; Inmunohistoquímica; Carcinoma mucinoso tubular y de células fusiformes; Mucinous tubular and spindle cell carcinomas (MTSC); Patología; Renal carcinoma
• ISSN: 0004-0614

Mucinous tubularand spindle cell carcinomas (MTSC) are a relativelyrare subtype of renal cell carcinoma (RCC) . Thesetumors are composed by tubular and spindle cellareas within a mucinous stroma. They are generallylow-grade nuclei tumors and limited to the kidney, sothey usually have a favorable prognosis. We report twonew cases of MTSC treated at our institution. MATERIALS AND METHODS: We reviewed therenal tumors surgery database of our hospital from2008 to 2019, selecting patients diagnosed with CMTF.We evaluated clinicopathological data and evolution ofthe patients. We also reviewed the published literatureto compare it with our findings. RESULTS: Two patients were included in the study,a 50-year-old male (case 1) and a 55-year-old female(case 2). The diagnosis was made by ultrasound asan incidental fi nding in case 1 and during the studyof fl ank pain in case 2. Treatment was surgical withpartial and radical nephrectomy respectively. After amean follow-up of 70 months, both patients are aliveand disease-free. CONCLUSION: Mucinous tubular and spindle cellcarcinomas (MTSC) is a rare renal tumor, approximatelytwo hundred cases have been published. Thereare questions yet to be answered about their diagnosisand behaviour so it is of utmost importance to reportnew cases in order to increase our knowledge and improvepatient care.