Effect of metformin added to chemotherapy on the survival of patients with acute lymphoblastic leukemia

Metformin has antineoplastic and cancer protective effects in vitro, sensitizing leukemia cells to chemotherapeutic agents, inducing apoptosis and cell cycle arrest. To assess the effect of metformin on the induction stage in patients with ALL and its impact on overall survival and relapse. We inclu...

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Bibliographic Details
Published in:Revista medíca de Chile Vol. 146; no. 7; pp. 846 - 853
Main Authors: Ramos Peñafiel, Christian, Olarte Carrillo, Irma, Ceron Maldonado, Rafael, Miranda Peralta, Enrique, Rozen Fuller, Etta, Kassack Ipiña, Juan Julio, Centeno Cruz, Federico, Collazo Jaloma, Juan, Martínez Tovar, Adolfo
Format: Journal Article
Language:Spanish
Published: Chile 01-07-2018
Online Access:Get full text
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