Effect of intrarectal povidone-iodine in the incidence of infectious complications after transrectal prostatic biopsy

• Published in: Archivos españoles de urología Vol. 65; no. 4; pp. 463 - 466
• Main Authors: Gil-Vernet Sedo, Jose Maria, Alvarez-Vijande García, Ricardo
• Format: Journal Article
• Language: English; Spanish
• Published: Spain 01-05-2012
• Subjects: Administration, Rectal; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local - administration & dosage; Bacterial Infections - epidemiology; Bacterial Infections - prevention & control; Biopsy, Needle - adverse effects; Ciprofloxacin - therapeutic use; Humans; Incidence; Male; Male Urogenital Diseases - epidemiology; Male Urogenital Diseases - prevention & control; Middle Aged; Povidone-Iodine - administration & dosage; Prospective Studies; Prostate - pathology; Prostatic Neoplasms - pathology; Ultrasonography, Interventional
• ISSN: 1576-8260

To assess the incidence of genitourinary infections associated with transrectal ultrasound-guided prostate biopsy (TRUS-BX) using endorectal povidone-iodine gel as a bactericidal agent.
We prospectively studied a total of 530 patients who were given 30g of 10% povidone-iodine intrarectally before TRUS-BX. Each patient received antibiotic prophylaxis with ciprofloxacin, starting the previous day (1g/day x 3 days), as well as cleansing enemas.
One patient (0.20%) presented with an E. coli acute bacterial epididymitis after biopsy.
In our study, the intrarectal use of 10% povidone-iodine gel in TRUS-BX is associated with a much lower rate of infectious complications compared to those described in recent literature.