Indications for transplantation and bridging procedures for primary hepatobiliary malignancies

Primary hepatobiliary malignancies are hepatocellular carcinoma, cholangiocarcinoma and the rare hepatocellular cholangiocarcinoma (mixed tumor). The indications for liver transplantation and the oncological prognosis differ considerably between these tumor entities. Treatment and decision making fo...

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Bibliographic Details
Published in:	Chirurg Vol. 89; no. 11; pp. 865 - 871
Main Authors:	Mittler, J, Heinrich, S, Lang, H
Format:	Journal Article
Language:	German
Published:	Germany 01-11-2018
Subjects:	Adult Bile Duct Neoplasms - therapy Bile Ducts, Intrahepatic Carcinoma, Hepatocellular - therapy Cholangiocarcinoma - therapy Humans Liver Neoplasms - therapy Liver Transplantation Hepatocellular carcinoma Primary liver cancer Mixed tumor Cholangiocarcinoma Organ allocation
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Summary:	Primary hepatobiliary malignancies are hepatocellular carcinoma, cholangiocarcinoma and the rare hepatocellular cholangiocarcinoma (mixed tumor). The indications for liver transplantation and the oncological prognosis differ considerably between these tumor entities. Treatment and decision making for these tumors are often complicated by an underlying chronic liver disease. The aim of this review is to delineate the indications for transplantation and bridging therapies for each cancer entity as well as to highlight some aspects pertinent to transplantation, such as the principles of organ allocation.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1433-0385
DOI:	10.1007/s00104-018-0733-z