Usefulness of C-reactive protein/albumin ratio as a predictor of new-onset atrial fibrillation in SARS coronavirus-2

• Published in: Biomarkers in medicine
• Main Authors: Kelesoglu, Saban, Yilmaz, Yucel, Ozkan, Eyup, Calapkorur, Bekir, Dursun, Zehra B, Ulu-Kilic, Aysegul, Elcık, Deniz
• Format: Journal Article
• Language: English
• Published: London, UK Future Medicine Ltd 01-09-2021
• ISSN: 1752-0363; 1752-0371
• DOI: 10.2217/bmm-2020-0866

Aim:
To investigate whether C-reactive protein/albumin ratio (CAR) has an association with new onset atrial fibrillation (NOAF) in SARS-CoV-2.
Materials & methods:
This study included 782 patients with SARS-CoV-2 infection, who were hospitalized in Turkey. The end point of the study was an occurrence of NOAF.
Results:
NOAF was identified in 41 patients (5.2%). Subjects who developed NOAF had a higher CAR compared with those who did not develop NOAF (p < 0.001). In the multivariate logistic regression analysis the CAR (odds ratio = 2.879; 95% CI: 1.063–7.793; p = 0.037) was an independent predictor of NOAF.
Conclusion:
 A high level of CAR in blood samples is associated with an increased risk of developing NOAF in SARS-CoV-2.