Cardiac arrest and secondary pulmonary oedema following accidental intramucosal injection of naphazoline in an adult

During neurosurgery for hypophysary adenoma under general anaesthesia in a prone position, a 34 year-old-women received accidental 6 ml intramucosal injection of lidocaine with naphazoline. The patient presented a severe bradycardia associated with a major increase in arterial blood pression followe...

Full description

Saved in:

Bibliographic Details
Published in:	Annales françaises d'anesthésie et de réanimation Vol. 22; no. 5; p. 477
Main Authors:	Villeret, I, Tellier, A C, Erhmann, S, Réa, D, Delalande, J P
Format:	Journal Article
Language:	French
Published:	France 01-05-2003
Subjects:	Adenoma - surgery Adrenergic alpha-Agonists - administration & dosage Adrenergic alpha-Agonists - adverse effects Adult Anesthesia, General Anesthetics, Local Blood Pressure - drug effects Bradycardia - chemically induced Female Heart Arrest - chemically induced Humans Lidocaine Medical Errors Naphazoline - administration & dosage Naphazoline - adverse effects Pituitary Neoplasms - surgery Pulmonary Edema - chemically induced
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	During neurosurgery for hypophysary adenoma under general anaesthesia in a prone position, a 34 year-old-women received accidental 6 ml intramucosal injection of lidocaine with naphazoline. The patient presented a severe bradycardia associated with a major increase in arterial blood pression followed by a brief cardiac arrest. She also presented a prolonged awakening and a pulmonary oedema, which lead to mechanical ventilation. The patient rapidly recovered a normal clinical state.
ISSN:	0750-7658
DOI:	10.1016/S0750-7658(03)00098-4