Cerebral Aspergillus abscess in immunocompetent patient

• Published in: Arquivos de neuro-psiquiatria Vol. 63; no. 4; pp. 1094 - 1098
• Main Authors: Pianetti Filho, Geraldo, Pedroso, Enio Roberto Pietra, Giannetti, Alexandre Varela, Darwich, Rogério
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil 01-12-2005
• Subjects: Adult; Amphotericin B - therapeutic use; Antifungal Agents - therapeutic use; Aspergillus; Aspergillus - isolation & purification; Brain Abscess - diagnosis; Brain Abscess - microbiology; Brain Abscess - therapy; Female; Fluconazole - therapeutic use; Follow-Up Studies; Humans; Immunocompetence; Intracranial Aneurysm - surgery; Neuroaspergillosis - diagnosis; Neuroaspergillosis - therapy; Postoperative Complications - microbiology; Tomography, X-Ray Computed; Treatment Outcome
• ISSN: 0004-282X
• DOI: 10.1590/S0004-282X2005000600033

We report an unusual case of brain aspergillosis with multiple recurrent abscess in a 40 year-old immunocompetent woman, with good therapeutical outcome. The patient presented a subarachnoid hemorrhage caused by a ruptured pericallosal artery aneurysm and was submitted to a craniotomy for aneurysm surgery. Five months later, she developed multiple Aspergillus cerebral abscess. Two craniotomies and amphotericin B became necessary during treatment. Fourteen years later, she is asymptomatic. Treatment of brain aspergillosis abscess implied the combination of both surgical and drug therapy with amphotericin B.