Contribution of dynamic interpretation of CA 125 measurements to the understanding of an atypical clinical case

The dynamic interpretation of the serum concentrations of markers is frequently used to calculate biological indicators of therapeutic efficiency and relapse. But analysis of marker kinetics can also help improve our understanding of the natural history of different types of cancer and their evoluti...

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Bibliographic Details
Published in:	Annales de biologie clinique (Paris) Vol. 66; no. 3; p. 333
Main Authors:	Riedinger, J-M, Mousseau, M, Gauchez, A-S
Format:	Journal Article
Language:	French
Published:	France 01-05-2008
Subjects:	Adult Biomarkers, Tumor - blood CA-125 Antigen - blood Female Humans Neoplasms, Glandular and Epithelial - blood Neoplasms, Glandular and Epithelial - drug therapy Neoplasms, Glandular and Epithelial - pathology Ovarian Neoplasms - blood Ovarian Neoplasms - drug therapy Ovarian Neoplasms - pathology
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Summary:	The dynamic interpretation of the serum concentrations of markers is frequently used to calculate biological indicators of therapeutic efficiency and relapse. But analysis of marker kinetics can also help improve our understanding of the natural history of different types of cancer and their evolution under treatment. This application is illustrated by an analysis of CA 125 kinetics measured in a patient with stage III ovarian cancer treated with multiple lines of chemotherapy and who had a survival time of 9 years.
ISSN:	0003-3898
DOI:	10.1684/abc.2008.0207