Kinetic study of acid-soluble DNA formation under the effect of DNase I

Kinetic study of acid-soluble DNA formation under the effect of DNase I

A mathematical model of acid-soluble DNA formation under the effect of DNase I was developed. The data from the kinetic analysis suggest that at the stage of 10-60% solubilization the number of breaks in DNA single strands seem to be linearly dependent on the increment of acid-soluble DNA. This stag...

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Published in:Ukrainskij biohimičeskij žurnal Vol. 52; no. 3; p. 369
Main Authors: Fedorova, T M, Miakisheva, V P, Grabarev, S P, Ryskukova, L N
Format: Journal Article
Language:Russian
Published: Ukraine 01-05-1980
Subjects:
Deoxyribonuclease I
Deoxyribonucleases - metabolism
DNA - biosynthesis
Endonucleases - metabolism
Kinetics
Mathematics
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Abstract A mathematical model of acid-soluble DNA formation under the effect of DNase I was developed. The data from the kinetic analysis suggest that at the stage of 10-60% solubilization the number of breaks in DNA single strands seem to be linearly dependent on the increment of acid-soluble DNA. This stage of acid-soluble DNA formation may be interpreted in terms of the monomolecular (pseudomonomolecular) reaction.
AbstractList A mathematical model of acid-soluble DNA formation under the effect of DNase I was developed. The data from the kinetic analysis suggest that at the stage of 10-60% solubilization the number of breaks in DNA single strands seem to be linearly dependent on the increment of acid-soluble DNA. This stage of acid-soluble DNA formation may be interpreted in terms of the monomolecular (pseudomonomolecular) reaction.
Author Grabarev, S P
Ryskukova, L N
Miakisheva, V P
Fedorova, T M
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  givenname: L N
  surname: Ryskukova
  fullname: Ryskukova, L N
BackLink https://www.ncbi.nlm.nih.gov/pubmed/6247798$$D View this record in MEDLINE/PubMed
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DocumentTitleAlternate Izuchenie kinetiki protsessa obrazovaniia kislotorastvorimykh produktov DNK pod deistviem DNK-azy I
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Snippet A mathematical model of acid-soluble DNA formation under the effect of DNase I was developed. The data from the kinetic analysis suggest that at the stage of...
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StartPage 369
SubjectTerms Deoxyribonuclease I
Deoxyribonucleases - metabolism
DNA - biosynthesis
Endonucleases - metabolism
Kinetics
Mathematics
Title Kinetic study of acid-soluble DNA formation under the effect of DNase I
URI https://www.ncbi.nlm.nih.gov/pubmed/6247798
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