Continuous blood glucose monitoring and infusion in freely mobile dogs (author's transl)

• Published in: Research in experimental medicine Vol. 179; no. 2; pp. 103 - 111
• Main Authors: Geisen, K, Reisig, E, Härtel, D
• Format: Journal Article
• Language: German
• Published: Germany 1981
• Subjects: Animals; Blood Glucose - analysis; Catheterization - veterinary; Dogs; Glucose - administration & dosage; Infusions, Parenteral; Insulin Infusion Systems; Monitoring, Physiologic - veterinary; Movement
• ISSN: 0300-9130
• DOI: 10.1007/BF01851978

With the system recently developed, continuous glucose determinations and programmed infusions are also possible in the freely mobile dog. The animal is kept in a dog box and wears a dog jacket to which a plastic plate is fitted. A bite- and twist-proof flexible hollow pipeline is connected rigidly to this plate. The pipeline goes through a hole in the centre of the roof of the dog box to a newly developed rotary adaptor system for three catheters. The rotary adaptor is fitted to a vertical sliding bar system with counter movement. The three catheters run along the inside of the hollow pipeline down to the animal's back where two of them connect to a double-lumen catheter (DLC) inserted in the jugular vein. Through one tube, heparin solution is transported to the tip of the DLC. There it is sucked back together with blood through the second tube and transported to the glucose analyser. Through the third catheter, insulin or glucose is infused into the other jugular vein. The flow of the extracorporeally heparinized blood is regular. Occlusion of the DLC does not occur. During a 24-h study period, 70 ml of blood are taken from the animal. The DLC is simple to manufacture and, if suitably developed, might also be used in humans instead of the usual rigid double-lumen plastic cannular system.