The potential and actual growth rate of breast cancer

Potential and actual rates of tumor growth were assayed in 13 patients with primary breast cancer. Potential growth rate was calculated according to proliferative activity as assessed by histoautoradiography whereas actual growth--on the basis of changes in tumor size observed on mammograms obtained...

Full description

Saved in:

Bibliographic Details
Published in:	Voprosy onkologij Vol. 37; no. 2; p. 174
Main Authors:	Moiseenko, V M, Semiglazov, V F, Klimashevskiĭ, V F, Semiachkina, S O, Chernomordikova, M F, Pozharisskiĭ, K M
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 1991
Subjects:	Autoradiography Breast - pathology Breast Neoplasms - diagnostic imaging Breast Neoplasms - physiopathology Cell Division Female Humans Lymphatic Metastasis Mammography Mitosis Time Factors Tritium
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Potential and actual rates of tumor growth were assayed in 13 patients with primary breast cancer. Potential growth rate was calculated according to proliferative activity as assessed by histoautoradiography whereas actual growth--on the basis of changes in tumor size observed on mammograms obtained through the course of the disease. Actual tumor doubling time proved 22.8 times longer (which means that tumors grew slower) than that suggested by proliferative activity. Cell loss at the average rate of 95.5% proved the main reason accounting for the difference. The proliferative activity in regional lymph node metastases measured in 3 patients simultaneously with the primary tumor assay was 3.9 times higher.
ISSN:	0507-3758